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While these fields were once studied in isolation, we now understand them as a singular, integrated system where mitochondrial health dictates the efficiency of fat oxidation

The AML Cells and Their Bone Marrow Microenvironment AML is a bone marrow disease (Figure 1) where the leukemic cells communicate with neighboring nonleukemic and AML-supporting cells through direct cellcell contact and the extracellular release of soluble mediators